Blood Clots

Blood clots form when blood thickens and clumps together, often to stop bleeding after an injury. While this process protects the body, it can also happen inside veins or arteries without any clear injury. Changes in blood flow, damage to blood vessels, or conditions that make blood more likely to clot can cause blood clots.

Health conditions like heart disease, cancer, or inherited clotting disorders can lead to clot formation. Lifestyle factors such as long periods of sitting, smoking, or carrying excess weight can also raise the risk. Certain medications, surgery, or pregnancy may also trigger clots.

Definition of Symptom

A blood clot, also called a thrombus, is a semi-solid mass that forms when blood changes from liquid to gel. This process helps heal injuries, but sometimes clots form inside vessels when they are not needed.

When a clot forms inside a vein, doctors call it a venous thrombus. A common example is deep vein thrombosis (DVT), which usually develops in the legs. If the clot breaks loose and travels, it becomes an embolism, which can block blood flow in the lungs or other organs.

An arterial clot forms in an artery, where blood carries oxygen to tissues. This type of clot can cut off circulation quickly and may lead to a heart attack or stroke. Arterial clots are often linked to atherosclerosis, where arteries narrow or harden.

Key Terms to Know

TermMeaning
ThrombusA stationary blood clot inside a vessel.
Venous thrombusClot in a vein, often in legs or pelvis.
Arterial thrombusClot in an artery, can block oxygen supply.
EmbolismA clot or piece of clot that travels and causes blockage elsewhere.
ThrombosisThe condition of having a clot inside a vessel.

Symptoms from blood clots depend on their location. Swelling and pain may occur with venous clots, while sudden chest pain or shortness of breath may signal a clot that has moved to the lungs.

Possible Causes/Diseases Condition

Many health conditions and lifestyle factors can cause blood clots. Some causes are temporary, while others are linked to long-term diseases. Cancer, diabetes, high blood pressure, high cholesterol, and obesity can increase clotting risk. Chronic inflammation and heart disease also make clots more likely to develop in veins or arteries. Some people inherit disorders like Factor V Leiden or prothrombin gene mutation, which make blood clot more easily.

These conditions may not always lead to clots but raise the chance of events such as deep vein thrombosis (DVT) or pulmonary embolism (PE). Hormones and pregnancy can affect clotting. Estrogen from birth control, hormone replacement therapy, or pregnancy itself can raise clotting risk. Pregnancy adds extra pressure on blood vessels, which can slow circulation and lead to DVT.

CategoryExamples
Medical ConditionsCancer, diabetes, obesity, heart disease
Genetic DisordersFactor V Leiden, prothrombin mutation
Hormonal FactorsPregnancy, birth control, hormone therapy

Other Non-Disease Causes

Certain everyday factors and situations can also increase risk. These are often linked to lifestyle, medications, or periods of limited movement.

  • Immobility plays a major role. Long hours of sitting during travel, extended bed rest after illness, or being confined due to paralysis can slow blood flow and raise the chance of clot formation.
  • Major surgery and hospitalization can increase risk. Surgery can damage blood vessels, while long recovery times often involve reduced movement. Both factors make clotting more likely.
  • Hormonal influences matter too. Birth control pills and hormone replacement therapy often contain estrogen, which can thicken the blood and promote clotting. Women using these treatments may face a higher risk, especially if other factors like obesity or smoking are present.
  • Lifestyle choices can add to the problem. Obesity and high blood pressure put extra strain on blood vessels, making clots more likely. Smoking is another risk, but quitting smoking can lower the chance of developing clots over time.
FactorHow It Contributes
ImmobilitySlows blood flow
Major surgeryVessel damage + less movement
HospitalizationLong bed rest
Birth control pillsEstrogen increases clotting
Hormone therapySimilar effect as pills
ObesityExtra strain on vessels
High blood pressureVessel damage risk
SmokingNarrows blood vessels

How It Causes the Symptom

When the body activates platelets and proteins to stop bleeding, blood clots form. This process is normal after an injury, but sometimes clots form inside vessels with no cut or wound. In these cases, the clot blocks normal blood flow and creates symptoms.

A clot in a vein or artery can cause pain, swelling, redness, or warmth in the affected area. If the clot moves, it may reach the lungs or brain, leading to more serious problems such as shortness of breath or sudden weakness.

Certain health conditions and lifestyle choices can increase the chance of clotting. Examples include surgery, immobility, smoking, high blood pressure, diabetes, and hormone therapy. These factors can damage blood vessels or make blood thicker, which triggers clot formation.

Key FactorHow It Contributes
PlateletsUnite efforts to effectively repair the vessel’s damage.
Vessel injuryInduces the activation of clotting proteins.
Thickened bloodImpairs circulation and increases the risk of blood clots.
Lack of movementReduces blood flow in legs.
AnticoagulantsHelp prevent blood clots from forming.

Without treatment, clots can grow larger and block more of the vessel.

Possible Complications

Blood clots can block normal blood flow and cause damage to organs or tissues. When this happens, the effects can be serious and may require urgent care. A clot in the brain can cut off oxygen and lead to sudden weakness, vision problems, or trouble speaking. A smaller, temporary blockage is called a transient ischemic attack (TIA), which often serves as a warning sign.

Clots in the heart’s arteries can trigger a heart attack. This happens when blood supply is reduced or stopped, leading to chest pain, shortness of breath, or pressure in the upper body. A clot that travels to the lungs can cause a pulmonary embolism. This may result in chest pain, rapid heartbeat, and breathing difficulty. It can become life-threatening if not treated quickly.

Blood clots can also affect other organs. For example, a clot in the kidneys may cause kidney failure, leading to fluid buildup and high blood pressure. A clot in the intestines can block blood flow and cause tissue damage.

Location of ClotPossible Outcome
BrainStroke, TIA
HeartHeart attack
LungsPulmonary embolism
KidneysKidney failure
IntestinesIschemic bowel

Even clots in the legs or arms can cause swelling and pain, and if they break loose, they may travel to the lungs.

When to Seek Medical Attention

Blood clots sometimes need treatment, but certain warning signs require urgent care. Ignoring these symptoms can increase the risk of serious complications. Seek immediate medical help if any of the following occur:

  • Sudden chest pain.
  • Shortness of breath or difficulty breathing.
  • Loss of speech or trouble understanding others.
  • Unexpected dizziness or fainting.
  • Swelling or pain in one leg, especially if it appears suddenly.

These symptoms can signal conditions like a blood clot in the leg or lungs. A clot in the lungs can block blood flow and cause life-threatening problems. Other concerning signs include:

  • Rapid or irregular heartbeat.
  • Coughing up blood.
  • Unexplained swelling that affects only one limb.
  • Skin that feels warm, red, or discolored around the affected area.
SymptomWhy It Matters
Chest painMay indicate a clot in the lungs or heart.
Shortness of breathIndicates that oxygen levels are diminished due to obstructed circulation.
Loss of speechCan signal a clot affecting the brain.
DizzinessMay point to reduced blood supply to the brain.

Anyone with these symptoms should call emergency services or go to the nearest hospital without delay.