What Causes Kidney Pain?

Kidney pain can be confusing because it often appears in the back or side where muscle pain also occurs. The most common causes include kidney stones, infections, dehydration, and injury. More serious causes, such as cysts, tumors, or urinary blockages, can also produce kidney pain.

Kidney pain often signals a disturbance in how the kidneys filter blood or drain urine. It may be accompanied by fever, nausea, urinary changes, or pain during urination. Early evaluation helps distinguish kidney pain from muscle or spine pain and guides appropriate treatment.

Definition of Symptom

Kidney pain originates from one or both kidneys, which sit just below the rib cage on either side of the spine. Because of their location, kidney pain is often called flank pain. It may feel dull, sharp, or constant, and it can radiate toward the lower abdomen or groin. In contrast to typical back or muscle pain, kidney pain frequently occurs with urinary symptoms or fever.

Common Symptoms That Suggest Kidney Pain

  • Pain in the flank, side, or lower back
  • Pain that may move to the abdomen or groin
  • Changes in urination, such as blood or burning
  • Fever, chills, or nausea in some cases
FeatureKidney PainBack or Muscle Pain
LocationBelow ribs, one or both sidesCenter or lower back
SpreadCan move to abdomen or groinUsually stays in back
Other symptomsUrinary changes, fever, nauseaStiffness, tenderness, soreness

If flank pain occurs with urinary changes, fever, or persistent nausea, it is more likely to reflect a kidney-related cause.

Possible Causes/Diseases Condition

Many conditions can cause kidney pain. Some are temporary and readily treatable, while others require urgent evaluation.

  • Kidney Stones: Mineral deposits obstruct urine flow, usually causing sharp, severe pain that can come in waves and may radiate to the groin.
  • Kidney Infection: Infection within the kidney typically causes deep aching pain, fever, chills, and urinary changes.
  • Polycystic Kidney Disease: Inherited cysts enlarge the kidneys and can cause swelling, chronic discomfort, and reduced function over time.
  • Hydronephrosis: Urine backs up and distends the kidney because of a stone, stricture, or other blockage.
  • Kidney Cancer or Tumors: May present with dull, persistent pain, blood in the urine, or a flank mass.
  • Urinary Tract Infection: Lower tract infections can spread to the kidneys and cause flank pain.
  • Kidney Injury: Blunt trauma or falls can bruise or lacerate the kidney, producing sudden pain.
  • Renal Vein Thrombosis: A clot in the renal vein can cause pain and reduced kidney function.
  • Advanced Kidney Failure: Later stages may involve pain along with swelling, fatigue, and changes in urine output.
ConditionTypical Features
Kidney stonesSharp, severe pain, nausea
Kidney infectionFever, chills, urinary changes
Polycystic kidney diseaseCysts, swelling, chronic pain
HydronephrosisKidney swelling, blockage symptoms
Kidney cancerDull pain, blood in urine
Kidney injuryPain after trauma
Renal vein thrombosisClot-related pain, dysfunction

Other Non-Disease Causes

Kidney-area pain may be caused by factors outside of disease. Distinguishing these helps avoid unnecessary treatment and directs attention to the true source. Muscle strain from heavy lifting, twisting, or strenuous exercise can mimic kidney pain. Pregnancy can increase pressure on the urinary tract and kidneys, causing flank discomfort without infection.

Dehydration concentrates urine and may irritate the urinary tract, sometimes causing mild kidney-area pain. Certain medications or supplements can affect the kidneys or irritate the urinary tract, especially without adequate hydration.

CauseCommon Signs
Muscle strainWorse with movement, tender
Pregnancy pressureFrequent urination, side pain
DehydrationCloudy or strong-smelling urine
Medication effectsBurning or urine changes

How It Causes the Symptom

Kidney pain arises when normal kidney function is disturbed. The kidneys filter waste and balance fluid and electrolytes. Any condition that blocks urine, inflames kidney tissue, or injures the organ can create pressure or swelling that triggers pain.

When a stone blocks urine flow, the kidney and collecting system distend. Stretching of the outer capsule and ureter produces sharp or constant flank pain that may radiate to the groin. Infections cause inflammation and swelling inside the kidney, which leads to deep aching pain, fever, and urinary changes. Trauma can cause bleeding or swelling that raises pressure within the kidney, producing sudden and intense discomfort.

Clinicians often begin with urine testing to look for blood, protein, white cells, or bacteria. Blood tests can show rising waste products or signs of infection. Imaging such as ultrasound or CT can reveal stones, blockages, cysts, tumors, or trauma.

Common Mechanisms Behind Kidney Pain

  • Kidney stones block urine and stretch the capsule
  • Infections inflame kidney tissue
  • Injury causes swelling or bleeding
  • Chronic disease gradually damages kidney structure

Possible Complications

Causes of kidney pain can progress and affect overall health if left untreated. Recognizing complications early helps protect kidney function. Infections may spread to the bloodstream and cause sepsis, which is a medical emergency.

Persistent obstruction from stones can damage the kidney, increase infection risk, and reduce function. Repeated injuries or chronic conditions can lead to chronic kidney disease and eventually kidney failure.

ComplicationPossible Outcome
SepsisLife-threatening infection
Blocked urine flowKidney damage or infection
Chronic kidney diseaseProgressive loss of function
High blood pressureHeart and vessel strain
Electrolyte imbalanceHeart rhythm and muscle issues
Abscess formationLocalized infection requiring drainage

When to Seek Medical Attention

Do not ignore kidney pain, especially when it is severe, sudden, or persistent. While some mild discomfort may resolve with rest and hydration, certain signs suggest urgent evaluation is needed. Seek medical attention promptly if you notice:

  • Fever or chills with back or flank pain
  • Nausea or vomiting that does not improve
  • Blood in the urine
  • Painful or frequent urination
  • Pain radiating to the groin or lower abdomen

If you have one-sided, unrelenting pain that does not improve with rest, you may have a blockage or infection that needs same-day assessment. Immediate care is especially important after a fall or accident that involves the back or side.

SymptomPossible Concern
High fever with back painKidney infection
Severe, wave-like flank painKidney stones
Blood in urineInfection, stones, injury
Sudden pain after traumaKidney injury

Persistent flank pain, especially with urinary changes or fatigue, should be evaluated by a healthcare professional. Early diagnosis helps protect kidney function and guides treatment to address the underlying cause.